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Gibco™ Mouse FGF-4 Recombinant Protein, PeproTech®
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Cantidad:
100 μg
2 x 500 μg
250 μg
25 μg
500 μg
5 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
25 microgramos
250 microgramos
5 microgramos
500 microgramos
paquete de 2
Descripción
450-57-1MG will be provided as 2 x 500 μg (450-57-500UG). Recombinant Murine FGF-4 is a 19.0 kDa protein consisting of 173 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
Especificaciones
Especificaciones
| Número de acceso | P11403 |
| Para utilizar con (aplicación) | Functional Assay |
| Formulación | protein with no preservative |
| ID de gen (Entrez) | 14175 |
| Peso molecular | 19 kDa |
| Nombre | Mouse FGF-4 |
| Cantidad | 100 μg |
| Fuente | E. coli |
| Estado normativo | RUO |
| Concentración de endotoxinas | <1 EU/ μg |
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