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Eurofins DiscoverX Met Protein, Active

Código de producto. 17380294
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Cantidad:
10 μg
250 μg
Tamaño de la unidad:
10 microgramos
250 microgramos
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Código de producto. 17380294

Marca: Eurofins DiscoverX 14526

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Description

Active, N-terminal His6-tagged recombinant human Met residues 974-end, for use in Kinase Assays.

MET tyrosine kinase is a high-affinity receptor for hepatocyte growth factor/scatter factor. Signaling via this receptor-ligand pair has been shown to affect a wide range of biological activities, including angiogenesis, cellular motility, growth, invasion, and morphogenic differentiation. Mutations in the MET tyrosine kinase receptor have been identified in both hereditary and sporadic forms of papillary renal carcinoma and implicated in tumor growth, invasion, and metastasis.

GenBank J02958. This construct contains the conflicts A1209G and V1290L with respect toGenBank J02958. Both conflicts are reported inGenBank BU595386, BQ315895 and BQ316491.

Specifications

Formulación mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Peso molecular 50 kDa
Cantidad 10 μg
Especie Human
Recombinante Recombinant
Etiqueta de proteína N-terminal 6His
Sistema de expresión Recombinant enzyme expressed in Sf21 insect cells
Forma de proteína Truncated
Grado de pureza o calidad ≥60%
Expresión Met, active
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