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Invitrogen™ Human MARK1 (MARK), GST Tag Recombinant Protein
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Cantidad:
10 μg
Tamaño de la unidad:
10 microgramos
Descripción
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length
MARK1 (MARK) is a serine/threonine kinase which is involved in cytoskeletal organization and biogenesis. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. MARK1 is involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
Especificaciones
Especificaciones
| Número de acceso | Q9P0L2 |
| Concentración | See Label |
| Para utilizar con (aplicación) | Kinase Assay |
| Formulación | 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5 |
| ID de gen (Entrez) | 4139 |
| Peso molecular | 116.5 kDa |
| Nombre | Human MARK1 (MARK), GST Tag |
| Cantidad | 10 μg |
| Estado normativo | For research use only. Not for use in diagnostic procedures |
| Alias de gen | AW491150; B930025N23Rik; ELKL motif serine/threonine-protein kinase 3; ELKL motif serine-threonine protein kinase 3; Emk3; KIAA1477; MAP/microtubule affinity regulating kinase 1; MAP/microtubule affinity-regulating kinase 1; MARK; MARK1; mark1 {ECO:0000312; microtubule affinity regulating kinase 1; mKIAA1477; mPar-1 c; PAR1 homolog c; Par1c; Par-1 c; RGD:619882}; serine/threonine-protein kinase MARK1 |
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