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Invitrogen™ Human MAPK8 (JNK1), His Tag Recombinant Protein
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Cantidad:
100 μg
10 μg
Tamaño de la unidad:
10 microgramos
100 microgramos
Descripción
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.
MAPK8 (JNK1) is activated by the presence of misfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity. It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
Especificaciones
Especificaciones
| Número de acceso | P45983 |
| Concentración | See Label |
| Para utilizar con (aplicación) | Kinase Assay |
| Formulación | 50mM tris with 2mM DTT, 0.05mM EDTA, 50% glycerol, 150mM NaCl, 0.05% Triton X-100 and no preservative; pH 7.5 |
| ID de gen (Entrez) | 5599 |
| Peso molecular | 47.6 kDa |
| Nombre | Human MAPK8 (JNK1), His Tag |
| Intervalo de pH | 7.5 |
| Método de purificación | Purified |
| Cantidad | 100 μg |
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