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Invitrogen™ Human MAPK8 (JNK1), His Tag Recombinant Protein

Código de producto. 10053082
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Cantidad:
1 mg
Tamaño de la unidad:
1 miligramo
Código de producto. Cantidad unitSize
10053082 1 mg 1 miligramo
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Código de producto. 10053082

Marca: Invitrogen™ PV3593

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Descripción

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

MAPK8 (JNK1) is activated by the presence of misfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity. It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P45983
Concentración See Label
Para utilizar con (aplicación) Kinase Assay
Formulación 50 mM tris with 0.05% Triton X-100, 0.05 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
ID de gen (Entrez) 5599
Peso molecular 47.6 kDa
Nombre Human MAPK8 (JNK1), His Tag
Cantidad 1 mg
Estado normativo For research use only. Not for use in diagnostic procedures
Alias de gen AI849689; c-Jun N-terminal kinase 1; FLJ12099; FLJ33785; JNK; JNK1; JNK1 beta1 protein kinase; jnk1a-1; JNK1A2; JNK21B1/2; JNK3; JNK3A; JNK-46; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAPK 10; MAPK 8; MAPK10; Mapk8; mapk8 protein; mapk8b; MGC50974; mitogen activated protein kinase 8; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8 b; MK10; OTTHUMP00000019552; p493F12; p54 gamma; p54bSAPK; Phospho-JNK; PRKM10; PRKM8; protein kinase JNK1; protein kinase mitogen-activated 8; SAPK gamma; SAPK1; SAPK1C; stress-activated protein kinase 1; stress-activated protein kinase 1 c; Stress-activated protein kinase JNK1; zgc:112379
Nombre común JNK1
Familia Quinasa MAP
Tipo de producto MAPK8 (JNK1) Recombinant Human Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína His-tag
Secuencia Full length
Contenido y almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Sistema de expresión Insect cells
Formulario Liquid
Grado de pureza o calidad 95% by SDS-PAGE
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