Epredia™ Lab Vision™ Surfactant Protein B (Precursor) Ab-1 Mouse Monoclonal Antibody, 200µg/mL, biotinylated, BSA and azide
Epredia™ Surfactant Protein B (Precursor) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.
Marca: Epredia™ MS-704-B1
Detalles adicionales : Peso : 1.00000kg
DescripciónPulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventillation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B. ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease.
Host Species: Mouse
Clone: SPB01; same as 1-2-A5-9
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Recombinant prosurfactant protein B
Molecular Weight: 42-46kDa
Positive Control: Lung adenocarcinoma
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
USA: RUO; Int'l: RUO
|Surfactant Protein B (Precursor) Ab-1|
|Biotinylated Ab with BSA and Azide|
|Immunofluorescence, Immunohistochemistry (Paraffin)|
|SPB01; same as 1-2-A5-9|
|Recombinant pro-surfactant protein B|
|Cancer and Tumor Biology|