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Surfactant Protein B (Precursor) Ab-1 Mouse Monoclonal Antibody, Epredia™
Epredia™ Surfactant Protein B (Precursor) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.
Marca: Epredia MS-704-B1
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Descripción
Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventillation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B. ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease.Host Species: Mouse
Clone: SPB01; same as 1-2-A5-9
Isotype: IgG2a/κ
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Recombinant prosurfactant protein B
Molecular Weight: 42-46kDa
Positive Control: Lung adenocarcinoma
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Immunofluorescence
Note:
USA: RUO; Int'l: RUO
Especificaciones
| Surfactant Protein B (Precursor) Ab-1 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| Cancer and Tumor Biology | |
| Human, Rat | |
| IgG2a κ |
| Immunofluorescence, Immunohistochemistry (Paraffin) | |
| SPB01; same as 1-2-A5-9 | |
| Biotin | |
| Recombinant pro-surfactant protein B | |
| RUO | |
| Primary | |
| Concentrated |