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Epredia™ Lab Vision™ DOG1 Rabbit Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ Dog1, Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio.

Marca:  Epredia™ RM-9132-S0

Detalles adicionales : Peso : 0.00170kg

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Código de producto. 12673797

  • 218.00€ / 0.10 ml

Fecha estimada de envío
21-06-2021

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Descripción

Descripción

DOG1 is a cell surface protein of unknown function selectively expressed in GIST. Among GIST cases with KIT mutations the DOG1 antibody identified 11% more cases than c-Kit antibody. DOG1 identifies vast majority of both c-Kit negative and PDGFRA mutated GIST cases that may still benefit from imatinib mesylate (Gleevac), an inhibitor of the kit tyrosin kinase. In addition, DOG1 immunoreactivity is seen in fewer cases of mesanchymal, epithelial tumors and melanomas when compared with c-Kit. The use of this highly sensitive and specific novel marker will increase the accuracy of GIST diagnosis.

Host Species: Rabbit

Clone: SP31

Isotype: IgG

Species Reactivity: Human. Others not known.

Immunogen: Synthetic peptide of human DOG1

Molecular Weight: 78 kDa

Positive Control: Gastrointestinal Stromal Tumors

Cellular Localization: Cytoplasmic and Membranous

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
Especificaciones

Especificaciones

DOG1
Monoclonal
Unconjugated
Concentrated
Synthetic peptide of human Dog1
100μL
Cancer and Tumor Biology
Primary
Human
Immunohistochemistry (Paraffin)
SP31
Culture Supernatant with Azide
Rabbit
IgG
IVD
Primary
Monoclonal
Videos
SDS
Documentos