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L-Selectin/CD62L Antibody (FMC46), Alexa Fluor™ 488, Novus Biologicals™

Código de producto. 18071464 Tienda Bio Techne Productos
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Cantidad:
0.1 mL
Tamaño de la unidad:
0.10 ml
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18071464 0.1 mL 0.10 ml
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Código de producto. 18071464 Proveedor Novus Biologicals N.º de proveedor NB10065388AF488

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Descripción

Mouse Monoclonal Antibody

L-Selectin/CD62L Monoclonal specifically detects L-Selectin/CD62L in Human, Bovine, Canine, Primate samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Product Image.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno L-Selectin/CD62L
Aplicaciones Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clasificación Monoclonal
Clon FMC46
Conjugado Alexa Fluor 488
Dilución Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Formulación 50mM Sodium Borate with 0.05% Sodium Azide
N.º de referencia del gen P14151
Alias de gen CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Símbolos de los genes SELL
Especie del huésped Mouse
Inmunógeno PHA stimulated lymphoblasts.
Método de purificación Protein G purified
Cantidad 0.1 mL
Estado normativo RUO
Disciplina de investigación Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells
Primario o secundario Primary
ID de gen (Entrez) 6402
Especificidad de la prueba NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
Especies diana Human, Bovine, Canine, Primate
Contenido y almacenamiento Store at 4C in the dark.
Formulario Purified
Isotype IgG2b
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For Research Use Only

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