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Inhibin beta A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 17524-1-AP-20UL
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Descripción
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.Especificaciones
Inhibin beta A | |
Polyclonal | |
Unconjugated | |
INHBA | |
Activin beta A chain, EDF, FRP, INHBA, Inhibin beta A chain, Inhibin beta-A, inhibin, beta A | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
16323, 29200, 3624 | |
-20°C | |
Liquid |
Western Blot, Immunoprecipitation | |
0.13 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P08476, P18331, Q04998 | |
INHBA | |
Peptide | |
20 μL | |
Primary | |
Rat, Human, Mouse | |
Antibody | |
IgG |