missing translation for 'onlineSavingsMsg'
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Descripción
The Insulin like growth factor-1, also known as Somatomedin-C is a growth factor which is structurally related to insulin and is an important regulator of growth and differentiation in various tissues and cell systems. Human IGF-1 is synthesized as two precursor isoforms with N- and alternate C-terminal propeptide. The two precursor isoforms are differentially expressed by various tissues. The proteolytic cleavage of the N- and C-terminal regions results in the mature IGF-1 protein which is identical between isoforms. IGF-1 binds to IGF-1 receptor and induces receptor autophosphorylation. This further phosphorylates Insulin receptor substrate -1 (IRS-1) and activates various downstream signaling pathways including the PI3-AKT, MAPK etc. (PMID: 17354613, 17113337, 29535161)
Especificaciones
Especificaciones
| Número de acceso | P05019 |
| Formulación | 1 x PBS pH 7.4 |
| ID de gen (Entrez) | 3479 |
| Peso molecular | 10 kDa |
| Cantidad | 1000 μg |
| Fuente | HEK293 |
| Requisitos de almacenamiento | Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.) |
| Concentración de endotoxinas | <1 EU/μg |
| Reactividad específica | Human |
| Recombinante | Recombinant |
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Título del producto
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