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Gibco™ Human TWEAK Receptor Recombinant Protein, PeproTech®

Código de producto. 17892863
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Cantidad:
100 μg
1 mg
250 μg
25 μg
500 μg
5 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
25 microgramos
250 microgramos
5 microgramos
500 microgramos
Código de producto. Cantidad unitSize
17892863 100 μg 100 microgramos
17852393 1 mg 1 miligramo
17852553 250 μg 250 microgramos
17822973 25 μg 25 microgramos
17862353 500 μg 500 microgramos
17812873 5 μg 5 microgramos
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Código de producto. 17892863

Marca: Gibco™ 31021100UG

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Description

Recombinant Protein

Recombinant Human soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full-length TWEAKR protein. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrate that this relatively small molecule is a fully transformed cell lines. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library. TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by binding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in the aorta and liver. It may also play a role in vascular cell migration and angiogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Número de acceso Q9NP84
Para utilizar con (aplicación) Functional Assay
Formulación protein with no preservative
ID de gen (Entrez) 51330
Peso molecular 5.6 kDa
Nombre Human TWEAK Receptor
Cantidad 100 μg
Fuente E. coli
Estado normativo RUO
Concentración de endotoxinas <1 EU/ μg
Alias de gen AI255180; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12 A; TNFRSF12A; Tumor necrosis factor receptor superfamily member 12 A; tumor necrosis factor receptor superfamily, member 12 A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14
Nombre común CD266
Símbolo de gen TNFRSF12A
Actividad biológica Determined by its ability to inhibit TWEAK-induced weak cell death of HT29 cells. The expected ED50 for this effect is 1.0-3.0 ug/ml
Conjugado Unconjugated
Recombinante Recombinant
Secuencia EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP
Contenido y almacenamiento -20°C
Sistema de expresión E. coli
Formulario Lyophilized
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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