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Gibco™ Human TIMP1 Recombinant Protein, PeproTech®

Código de producto. 17823813
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Cantidad:
100 μg
10 μg
1 mg
250 μg
2 μg
500 μg
50 μg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
2 microgramos
250 microgramos
50 microgramos
500 microgramos
Código de producto. Cantidad unitSize
17823813 1 mg 1 miligramo
17863873 100 μg 100 microgramos
17834303 10 μg 10 microgramos
17853873 250 μg 250 microgramos
17854303 2 μg 2 microgramos
17894233 500 μg 500 microgramos
17893873 50 μg 50 microgramos
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Código de producto. 17823813

Marca: Gibco™ 410011MG

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Descripción

Recombinant Protein

Recombinant Human TIMP-1 is a 20.6 kDa protein containing 184 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P01033
Para utilizar con (aplicación) ELISA, Functional Assay, Western Blot
Formulación protein with no preservative
ID de gen (Entrez) 7076
Peso molecular 20.6 kDa
Nombre Human TIMP1
Cantidad 1 mg
Fuente E. coli
Estado normativo RUO
Concentración de endotoxinas <1 EU/ μg
Alias de gen CLGI; collagenase inhibitor; Collagenase inhibitor 16C8 fibroblast; EG-1; Embryogenin-1; EPA; EPO; erythroid potentiating activity; erythroid-potentiating activity; Fibroblast collagenase inhibitor; FLJ90373; HCI; Metalloproteinase inhibitor; metalloproteinase inhibitor 1; metalloproteinase tissue inhibitor; metalloproteinase tissue inhibitor 1; MMP inhibitor; RP1-230G1.3; Timp; TIMP 1; TIMP metallopeptidase inhibitor 1; TIMP1; TIMP-1; TIMP-1 protein; tissue inhibitor of matrix metalloproteinase-1; tissue inhibitor of metal proteinases; tissue inhibitor of metallopeptidase 1; tissue inhibitor of metalloproteinase; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); tissue inhibitor of metalloproteinase-1; tissue inhibitor of metalloproteinases; tissue inhibitor of metalloproteinases 1; TPA-induced protein; TPA-S1
Nombre común TIMP1
Símbolo de gen TIMP1
Actividad biológica TIMP-1 activity was measured by its ability to inhibit human MMP-1-induced hydrolysis of a chromogenic peptide substrate at room temperature. Half maximal inhibition was obtained (at a TIMP-1 concentration of approximately 0.5 ug/ml, when using an MMP-1 concentration of 1.6 ug/ml)
Conjugado Unconjugated
Recombinante Recombinant
Secuencia CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIA
Contenido y almacenamiento -20°C
Sistema de expresión E. coli
Formulario Lyophilized
Grado de pureza o calidad ≥ 95% by SDS-PAGE gel and HPLC analyses.
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