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Gibco™ Human TACI Recombinant Protein, PeproTech®

Código de producto. 17822183
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Cantidad:
100 μg
2 x 500 μg
20 μg
250 μg
500 μg
5 μg
Unit Size:
1 miligramo
100 microgramos
20 microgramos
250 microgramos
5 microgramos
500 microgramos
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Product Code. 17822183

Brand: Gibco™ 310175UG

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Description

Recombinant Protein

310-17-1MG will be provided as 2 x 500 μg (310-17-500UG). Recombinant Human TACI is a soluble 159 amino acid polypeptide (17.8 kDa) comprising the TNFR homologous, cysteine-rich extracellular domain of the TACI protein. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
TRUSTED_SUSTAINABILITY

Specifications

Número de acceso O14836
Para utilizar con (aplicación) ELISA, Functional Assay, Western Blot
Formulación protein with no preservative
ID de gen (Entrez) 23495
Peso molecular 17.8 kDa
Nombre Human TACI
Cantidad 5 μg
Fuente E. coli
Estado normativo RUO
Concentración de endotoxinas <1 EU/ μg
Alias de gen 1200009E08Rik; CD267; CVID; CVID2; IGAD2; NEWGENE_1595998; RYZN; TACI; TNF receptor superfamily member 13 B; Tnfrsf13b; TNFRSF14B; transmembrane activator and calcium-modulating and cyclophilin ligand interactor; transmembrane activator and CAML interactor; tumor necrosis factor receptor 13 B; tumor necrosis factor receptor superfamily member 13 B; tumor necrosis factor receptor superfamily, member 13 B
Nombre común TACI
Símbolo de gen TNFRSF13B
Actividad biológica Determined by its ability to block human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 ug/ml
Conjugado Unconjugated
Recombinante Recombinant
Secuencia SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQV
Contenido y almacenamiento -20°C
Sistema de expresión E. coli
Formulario Lyophilized
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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