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STEMCELL Technologies Human Recombinant NGF-beta
Descripción
- Nerve growth factor (NGF)-beta is a prototypical member of the neurotrophin family and has a role in the survival and growth of neural cells, regulating cell growth, promoting differentiation into neurons, and neuron migration
- The beta subtype of NGF is biologically active in comparison to the alpha-2 and gamma-2 subtypes
- NGF-beta in its secreted form can bind to tyrosine kinase A (TrkA) receptor with high affinity and to p75 (NTR) with low affinity (Levi & Alemà; Sofroniew et al.) NGF has been shown to possess pro-inflammatory and pro-fibrogenic properties (Micera et al.) It has also been shown that overexpression of NGF-beta promotes differentiation of bone marrow mesenchymal stem cells into neurons through regulation of AKT and MAPK pathways (Yuan et al.)
Especificaciones
Especificaciones
| Nombre | Beta-nerve growth factor, beta-NGF, nerve growth factor (beta polypeptide) |
| Cantidad | 20 μg |
| Tipo de célula | Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons |
| Grado de pureza o calidad | ≥95% |
Título del producto
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