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STEMCELL Technologies Human Recombinant Betacellulin
Descripción
- Betacellulin is a member of the epidermal growth factor (EGF) family, and signals through EGF receptor and ERBB4
- It activates ERK and AKT pathways, which induces neural stem cell proliferation and prevents spontaneous differentiation in culture
- Betacellulin stimulates the expansion of neural stem cells, transit-amplifying cells, and neuroblasts derived from subventricular zone and dentate gyrus
- It is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells
- Betacellulin down-regulates E-cadherin expression in ovarian cancer cell lines via MEK/ERK1/2 and PI3K/AKT signaling pathways, thus increasing cell migration
- It is a modulator of interferon (IFN) response and enhances anti-viral effects of IFN
- Betacellulin is expressed in pancreatic α cells, β cells, and duct cells
Especificaciones
Especificaciones
| Cantidad | 1000 μg |
| Tipo de célula | Endoderm, PSC-Derived; Neural Stem and Progenitor Cells |
| Grado de pureza o calidad | ≥95% |
Título del producto
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