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Gibco™ Human IGF-BP3 Recombinant Protein, PeproTech®

Código de producto. 17820453
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Cantidad:
100 μg
1 mg
250 μg
25 μg
500 μg
5 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
25 microgramos
250 microgramos
5 microgramos
500 microgramos
Código de producto. Cantidad unitSize
17820453 25 μg 25 microgramos
17831233 100 μg 100 microgramos
17880173 1 mg 1 miligramo
17881733 250 μg 250 microgramos
17820933 500 μg 500 microgramos
17851023 5 μg 5 microgramos
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Artikelnummer. 17820453

Marke: Gibco™ 1000825UG

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Beschreibung

Recombinant Protein

Recombinant Human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

IGFBP3 is a gene that belongs to the insulin-like growth factor binding protein (IGFBP) family. The gene encodes a protein that contains both an IGFBP domain and a thyroglobulin type-I domain. This protein is known to form a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. The complex circulates in the plasma and prolongs the half-life of IGFs while also altering their interaction with cell surface receptors. Various isoforms of the gene have been identified through alternate transcriptional splice variants. Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Acid-Labile Subunit Deficiency.
TRUSTED_SUSTAINABILITY

Spezifikation

Número de acceso P17936
Para utilizar con (aplicación) ELISA, Functional Assay, Western Blot
Formulación protein with no preservative
ID de gen (Entrez) 3486
Peso molecular 28.8 kDa
Nombre Human IGF-BP3
Cantidad 25 μg
Fuente E. coli
Estado normativo RUO
Concentración de endotoxinas <1 EU/ μg
Alias de gen acid stable subunit of the 140 K IGF complex; AI649005; binding protein 29; binding protein 53; BP53; BP-53; Growth hormone dependent binding protein; growth hormone-dependent binding protein; I79_011450; IBP3; IBP-3; IGF binding protein 3; IGF-binding protein 3; IGFBP; Igfbp3; IGF-BP3; IGFBP-3; IGgfbp3; Insulin like growth factor binding protein; insulin like growth factor binding protein 3; insulin-like growth factor binding protein 3; Insulin-like growth factor binding protein 3 precursor; insulin-like growth factor-binding protein (IGF-BP3); insulin-like growth factor-binding protein 3; tcag7.703
Nombre común IGFBP3
Símbolo de gen IGFBP3
Actividad biológica The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7. The expected ED50 for this effect is ≤ 0.2 ug/ml in presence of 15 ng/ml of human IGF-II.
Conjugado Unconjugated
Recombinante Recombinant
Secuencia GASSGGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG EVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK
Contenido y almacenamiento -20°C
Sistema de expresión E. coli
Formulario Lyophilized
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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