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Invitrogen™ Human ICAM-1 (CD54) Recombinant Protein

Código de producto. 11578961
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Cantidad:
10 μg
Tamaño de la unidad:
10 microgramos
Código de producto. Cantidad unitSize
11578961 10 μg 10 microgramos
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Código de producto. 11578961

Marca: Invitrogen™ RP75641

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Beskrivelse

Recombinant Protein

RP-75641 contains purified recombinant human ICAM-1 protein with an N-terminal hexahistidine tag. RP-75641 may be used as a positive control in many immunological assays.

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
TRUSTED_SUSTAINABILITY

Tekniske data

Número de acceso P05362
Concentración 0.165 mg/mL
Para utilizar con (aplicación) Control, Western Blot
Formulación 20 mM tris HCl, PBS with 50% glycerol and no preservative; pH 8
ID de gen (Entrez) 3383
Nombre Human ICAM-1 (CD54)
Intervalo de pH 8.0
Cantidad 10 μg
Fuente E. coli
Inmunógeno N/A
Estado normativo RUO
Alias de gen BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells
Nombre común ICAM-1 (CD54)
Símbolo de gen ICAM1
Conjugado Unconjugated
Especie E. coli
Recombinante Recombinant
Etiqueta de proteína His-tag
Secuencia Amino acids Gln28- Val482 containing an N-terminal His-tag
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Sistema de expresión E. coli
Formulario Liquid
Subtipo de proteína Recombinant
Grado de pureza o calidad >95%, by SDS-PAGE under reducing conditions
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