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Gibco™ Human Growth Hormone Recombinant Protein, PeproTech®
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Cantidad:
100 μg
10 μg
1 mg
250 μg
500 μg
50 μg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
250 microgramos
50 microgramos
500 microgramos
Descripción
Recombinant Human Growth Hormone is a 22.3 kDa, single, non-glycosylated polypeptide chain containing 192 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
Especificaciones
Especificaciones
| Número de acceso | P01241 |
| Para utilizar con (aplicación) | Functional Assay |
| Formulación | protein with no preservative |
| ID de gen (Entrez) | 2688 |
| Peso molecular | 22.3 kDa |
| Nombre | Human Growth Hormone |
| Cantidad | 250 μg |
| Fuente | E. coli |
| Estado normativo | RUO |
| Concentración de endotoxinas | <1 EU/ μg |
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