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Gibco™ Human Flt-3 Ligand (FLT3L) Recombinant Protein

Código de producto. 10365588
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Cantidad:
100 μg
10 μg
1 mg
25 μg
Tamaño de la unidad:
cada uno
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Código de producto. 10365588

Marca: Gibco™ PHC9411

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Recombinant Protein

Carrier-Free Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in sterile, distilled water or appropriate buffered solution containing 0.1% BSA to regain full activity. Apportion there constituted protein into working aliquots and store at ≤-20°C. Make any further dilutions of the reconstituted protein in buffered solution containing a carrier protein, such as PBS + 0.1% BSA. Storage: Store the lyophilized protein at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤-20°C. Avoid repeated freeze-thaw cycles.

FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P49771
Para utilizar con (aplicación) Bioactivity
Formulación Protein with no preservative
ID de gen (Entrez) 2323
Peso molecular 35 kDa
Nombre Human Flt-3 Ligand (FLT3L)
Método de purificación Purified
Cantidad 100 μg
Requisitos de almacenamiento 4°C
Estado normativo RUO
Concentración de endotoxinas <0.1 ng/μg
Alias de gen FL; Flt 3 ligand; Flt3; Flt3 L; Flt3 ligand; Flt3l; Flt3lg; fms related receptor tyrosine kinase 3 ligand; fms related tyrosine kinase 3 ligand; FMS-like tyrosine kinase 3 ligand; fms-related tyrosine kinase 3; fms-related tyrosine kinase 3 ligand; H-FLT-3-L; Ly72L; M-FLT-3-L; NEWGENE_2322792; SL cytokine
Nombre común FLT3LG
Símbolo de gen FLT3LG
Actividad biológica ED50 ≤ 5 ng/mL; determined by the dose-dependent proliferation of human OCI-AML5 cells.
Tipo de producto Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Secuencia TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTAPQP
Contenido y almacenamiento 4°C
Clasificación Carrier-Free
Actividad ED50 ≤ 5 ng/mL; determined by the dose-dependent proliferation of human OCI-AML5 cells.
Nivel de endotoxinas <0.1 ng/μg
Reactividad Human
Condiciones de envío Wet Ice
Sistema de expresión HEK293 cells
Familia de proteínas Growth Factors & Receptors
Forma de proteína Recombinant, Ligand
Formulario Lyophilized
Subtipo de proteína FLT-3 Ligand
Categoría de investigación Signal Transduction, Stem Cell Research, Oncology
Línea de productos Gibco
Grado de pureza o calidad >95% by SDS-PAGE
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