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Invitrogen™ Human ESRP2 (aa 164-249) Control Fragment Recombinant Protein
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Descripción
Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.
Especificaciones
Especificaciones
| Número de acceso | Q9H6T0 |
| Concentración | ≥5.0 mg/mL |
| Para utilizar con (aplicación) | Blocking Assay, Control |
| Formulación | 1 M urea, PBS with no preservative; pH 7.4 |
| ID de gen (Entrez) | 80004 |
| Nombre | Human ESRP2 (aa 164-249) Control Fragment |
| Cantidad | 100 μL |
| Estado normativo | RUO |
| Alias de gen | 9530027K23Rik; Epithelial splicing regulatory protein 2; ESRP2; PP7059; RBM35B; RGD1310855; RNA binding motif protein 35 A; RNA binding motif protein 35 B; RNA-binding motif protein 35 B; RNA-binding protein 35 B |
| Nombre común | ESRP2 |
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