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Gibco™ Human EPO (Erythropoietin) Recombinant Protein, PeproTech®

Product Code. 17830773
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Cantidad:
100 μg
10 μg
1 mg
250 μg
500 μg
50 μg
Unit Size:
1 miligramo
10 microgramos
100 microgramos
250 microgramos
50 microgramos
500 microgramos
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Product Code. Cantidad unitSize
17830773 100 μg 100 microgramos
17831643 10 μg 10 microgramos
17810463 1 mg 1 miligramo
17871643 250 μg 250 microgramos
17850553 500 μg 500 microgramos
17801043 50 μg 50 microgramos
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Product Code. 17830773 Supplier Gibco™ Supplier No. 10064100UG

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Recombinant Protein

PeproTech's Human EPO contains 166 amino acid residues and has a calculated molecular weight of approximately 18.4 kDa. As a result of glycosylation, Recombinant Human EPO migrates with an apparent molecular mass of 37.0 kDa by SDS-PAGE gel, under reducing and non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.
TRUSTED_SUSTAINABILITY

Specifications

Número de acceso P01588
Para utilizar con (aplicación) ELISA, Functional Assay, Western Blot
Formulación protein with no preservative
ID de gen (Entrez) 2056
Peso molecular 18.4 kDa
Nombre Human EPO (Erythropoietin)
Cantidad 100 μg
Fuente CHO cells
Estado normativo RUO
Concentración de endotoxinas <1 EU/ μg
Alias de gen EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2
Nombre común Epo
Símbolo de gen EPO
Actividad biológica Determined by a cell proliferation assay using TF-1 cells. The expected ED50 for this effect is 0.8-1.0 ng/ml
Conjugado Unconjugated
Recombinante Recombinant
Secuencia APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGDR
Contenido y almacenamiento -20°C
Sistema de expresión CHO cells
Formulario Lyophilized
Grado de pureza o calidad ≥ 90% by SDS-PAGE gel and HPLC analyses.
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