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Gibco™ Human BMP-4, Animal-Free Recombinant Protein, PeproTech®

Código de producto. 17873783
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Cantidad:
100 μg
10 μg
2 x 500 μg
500 μg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
500 microgramos
paquete de 2
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Código de producto. Cantidad unitSize
17873783 500 μg 500 microgramos
17803593 2 x 500 μg 1 miligramo
30087502 2 x 500 μg paquete de 2
17883503 10 μg 10 microgramos
17823023 100 μg 100 microgramos
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Código de producto. 17873783 Proveedor Gibco™ N.º de proveedor AF12005ET500UG

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2200.00 EUR hasta el 2026-06-30
MEJOR PRECIO en promoción! Use el código promocional "27928" para aplicar la oferta.
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Descripción

Recombinant Protein

AF-120-05ET-1MG will be provided as 2 x 500 μg (AF-120-05ET-500UG). PeproTech's E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 107 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor, and includes a N-terminal Met residue. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 24.2 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P12644
Para utilizar con (aplicación) Control, Bioactivity
Formulación Protein with no preservative
ID de gen (Entrez) 652
Peso molecular 24.2 kDa
Nombre Human BMP-4, Animal-Free
Método de purificación Purified
Cantidad 500 μg
Fuente E. coli
Requisitos de almacenamiento -20°C
Estado normativo RUO
Concentración de endotoxinas <0.1 EU/μg
Alias de gen BMP; BMP2B; BMP-2B; Bmp2b1; Bmp2b-1; Bmp4; Bmp-4; BOMPR4A; Bone morphogenetic protein; Bone morphogenetic protein 2B; bone morphogenetic protein 4; bone morphogenetic protein 4 preproprotein; DVR4; Dvr-4; MCOPS6; OFC11; ZYME
Nombre común BMP4
Símbolo de gen BMP4
Actividad biológica Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Secuencia MKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SMLYLDEYDK VVLKNYQEMV VEGCGCR
Contenido y almacenamiento -20°C
Actividad Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
Sistema de expresión E. coli
Formulario Lyophilized
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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