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Invitrogen™ Human B7-H3 (CD276) Fc Chimera Recombinant Protein
Descripción
It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (500 μL) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV.
CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing. CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.
Especificaciones
Especificaciones
| Número de acceso | Q5ZPR3 |
| Concentración | 0.25 mg/mL |
| Para utilizar con (aplicación) | Control, Neutralization |
| Formato | Lyophilized |
| Formulación | PBS with 5% mannitol, 5% trehalose, 0.01% Tween 80 and no preservative; pH 7.4 |
| ID de gen (Entrez) | 80381 |
| Peso molecular | 109.5 kDa |
| Nombre | Human B7-H3 (CD276) Fc Chimera |
| Intervalo de pH | 7.4 |
| Método de purificación | Purified |
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Título del producto
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