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Gibco™ Human Apo-SAA Recombinant Protein, PeproTech®

Código de producto. 17861883
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Cantidad:
100 μg
10 μg
1 mg
250 μg
500 μg
50 μg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
250 microgramos
50 microgramos
500 microgramos
Código de producto. Cantidad unitSize
17861883 100 μg 100 microgramos
17860163 10 μg 10 microgramos
17831213 1 mg 1 miligramo
17840243 250 μg 250 microgramos
17830623 500 μg 500 microgramos
17871813 50 μg 50 microgramos
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Código de producto. 17861883

Marca: Gibco™ 30013100UG

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Descripción

Recombinant Protein

Recombinant Apo-SAA is a consensus SAA molecule corresponding to human Apo-SAA1alpha, except for the presence of an N-terminal methionine, the substitution of asparagine for aspartic acid at position 60, and arginine for histidine at position 71 (the latter two substituted residues are present in Apo-SAA2beta). The calculated molecular weight of Recombinant Human Apo-SAA is 11.7 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The serum amyloid A family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma and constitutive SAAs. Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations; SAA rises earlier and more sharply than CRP. Recently, a broader view of SAA expression and function has been emerging.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P0DJI8
Para utilizar con (aplicación) Control, Bioactivity
Formulación Protein with no preservative
ID de gen (Entrez) 6288
Peso molecular 11.7 kDa
Nombre Human Apo-SAA
Método de purificación Purified
Cantidad 100 μg
Fuente E. coli
Requisitos de almacenamiento -20°C
Estado normativo RUO
Concentración de endotoxinas <1 EU/μg
Alias de gen amyloid a; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA1; Saa-1; Saa2; serum amyloid A; serum amyloid A 1; serum amyloid A 2; serum amyloid A protein; serum amyloid A1; Serum amyloid A1 protein; Serum amyloid A-1 protein; serum amyloid A-like protein; Serum amyloid protein A(2-102); Serum amyloid protein A(2-103); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(4-101); Serum Amyloid-A; TP53I4; tumor protein p53 inducible protein 4
Nombre común SAA
Símbolo de gen SAA1
Actividad biológica Tested by its ability to down-regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4 uM. * Schreiber, BM. et al. Biochem J. 1999 Nov 15; 344 Pt 1:7-13
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Secuencia MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS NARENIQRFF GRGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
Contenido y almacenamiento -20°C
Actividad Tested by its ability to down-regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4 uM. * Schreiber, BM. et al. Biochem J. 1999 Nov 15; 344 Pt 1:7-13
Sistema de expresión E. coli
Formulario Lyophilized
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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