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Invitrogen™ Human GSK-3B (GSK3 beta), His Tag Recombinant Protein
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Cantidad:
10 μg
1 mg
Tamaño de la unidad:
1 miligramo
10 microgramos
Descripción
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.
GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.
Especificaciones
Especificaciones
| Número de acceso | P49841 |
| Concentración | See Label |
| Para utilizar con (aplicación) | Kinase Assay |
| Formulación | 50mM tris with 150mM NaCl, 0.01% Triton X-100, 2mM DTT, 50% glycerol, 0.5mM EDTA and no preservative; pH 7.5 |
| ID de gen (Entrez) | 2932 |
| Peso molecular | 53.1 kDa |
| Nombre | Human GSK-3B (GSK3 beta), His Tag |
| Intervalo de pH | 7.5 |
| Método de purificación | Purified |
| Cantidad | 10 μg |
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