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FEM1B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 19544-1-AP-20UL
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Descripción
The antibody recognize the C-term of FEM1B.
Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1-b. F1Aalpha/FEM1-b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase. FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues.Especificaciones
| FEM1B | |
| Polyclonal | |
| Unconjugated | |
| FEM1B | |
| F1A alpha, F1AA, fem 1 homolog b (C. elegans), FEM1 beta, FEM1B, FIAA, KIAA0396, Protein fem 1 homolog B | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 10116, 14155, 315745 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Western Blot, Immunofluorescence | |
| 0.16 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P0C6P7, Q9UK73, Q9Z2G0 | |
| Fem1b | |
| Peptide | |
| 20 μL | |
| Primary | |
| Mouse, Rat, Human | |
| Antibody | |
| IgG |