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CD8 Antibody (C8/468), FITC, Novus Biologicals™

Product Code. 18173532 Shop All Bio Techne Products
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Cantidad:
0.1 mL
Unit Size:
0.10 ml
Product Code. Cantidad unitSize
18173532 0.1 mL 0.10 ml
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Product Code. 18173532

Brand: Novus Biologicals NBP234589F

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Description

Mouse Monoclonal Antibody

CD8 Monoclonal specifically detects CD8 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno CD8
Aplicaciones Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clasificación Monoclonal
Clon C8/468
Conjugado FITC
Dilución Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Formulación PBS with 0.05% Sodium Azide
Alias de gen CD8, CD8a molecule, LEU2, p32
Símbolos de los genes CD8A
Especie del huésped Mouse
Inmunógeno Human CD8 recombinant protein (Uniprot: P01732 )
Método de purificación Protein A or G purified
Cantidad 0.1 mL
Estado normativo RUO
Disciplina de investigación Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Phospho Specific, Signal Transduction, Stem Cell Markers
Primario o secundario Primary
Especificidad de la prueba CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Especies diana Human
Contenido y almacenamiento Store at 4°C in the dark.
Isotype IgG1 κ
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