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CD74 Antibody (LN-2), DyLight 650, Novus Biologicals™

Código de producto. 18103913 Tienda Bio Techne Productos
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Cantidad:
0.1 mL
Tamaño de la unidad:
0.10 ml
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18103913 0.1 mL 0.10 ml
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Código de producto. 18103913 Proveedor Novus Biologicals N.º de proveedor NBP233088C

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Mouse Monoclonal Antibody

CD74 Monoclonal specifically detects CD74 in Human, Mouse, Baboon, Rat (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno CD74
Aplicaciones Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clasificación Monoclonal
Clon LN-2
Conjugado DyLight 650
Dilución Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Alias de gen CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated), CD74 molecule, major histocompatibility complex, class II invariant chain, DHLAGgamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, Ii, MHC HLA-DR gamma chain, p33
Símbolos de los genes CD74
Especie del huésped Mouse
Inmunógeno SU-DHL-4 lymphoma cells were used as the immunogen for the CD74 antibody
Peso molecular del antígeno 37 kDa
Método de purificación Protein A or G purified
Cantidad 0.1 mL
Estado normativo RUO
Disciplina de investigación Immunology
Primario o secundario Primary
ID de gen (Entrez) 972
Especificidad de la prueba It recognizes a protein of ∼35kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
Especies diana Human, Mouse, Baboon, Rat (Negative)
Contenido y almacenamiento Store at 4C in the dark.
Formulario Purified
Isotype IgG1 κ
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