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CD4 Rat, anti-Mouse, PerCP-Cyanine5.5, Clone: RM4-5, STEMCELL Technologies
Rat Monoclonal Antibody
Marca: Stemcell Technologies 60017PS.1
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Descripción
- The RM4-5 antibody reacts with mouse CD4, an ∼55 kDa single-chain type 1 transmembrane glycoprotein and member of the immunoglobulin (Ig) superfamily; CD4 contains four extracellular Ig-like domains
- CD4 is expressed at relatively high levels by most thymocytes and a subpopulation of T cells (T helper/inducer cells), and at lower levels on dendritic cells
- CD4 binds to a non-polymorphic region of MHC II and acts as a co-receptor to the T cell receptor (TCR) in MHC II-restricted antigen recognition by enhancing the avidity of the association between the TCR and MHC II-antigen complex
- Binding of the RM4-5 antibody to CD4 inhibits ligand binding in vitro; binding of the RM4-5 antibody can be blocked by the clone GK1.5 antibody
- This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD4+ T Cell Isolation Kit (Catalog #19852) and EasySep™ Mouse CD25 Regulatory T Cell Positive Selection Kit (Catalog #18782)
Especificaciones
| CD4 | |
| Monoclonal | |
| PerCP-Cyanine5.5 | |
| 25 μg | |
| Mouse | |
| T Cells, T Cells, CD4+, T Cells, Regulatory |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| RM4-5 | |
| Rat | |
| Primary | |
| IgG2a κ |