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CD36 Antibody (185-1G2), PE, Novus Biologicals™
Mouse Monoclonal Antibody
Marca: Novus Biologicals NBP2-95271PE
Código de producto. 18027256
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650.00€
614.25€ / 0.10 ml
Ahorro 35.75€
5% Descuento
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Descripción
CD36 Monoclonal specifically detects CD36 in Human samples. It is validated for Flow Cytometry.
Especificaciones
| CD36/SR-B3 | |
| Monoclonal | |
| PE | |
| CD36 antigen, CD36 molecule (thrombospondin receptor), FA6-152, FATCHDS7, Fatty acid translocase, Glycoprotein IIIb, GP3Bthrombospondin receptor), GPIIIB, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, Platelet collagen receptor, platelet glycoprotein 4, Platelet glycoprotein IV, scavenger receptor class B, member 3, Thrombospondin receptor | |
| Stimulated human leukocytes | |
| 0.1 mL | |
| Cancer, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Immunology, Lipid and Metabolism, Stem Cell Markers | |
| 948 | |
| Human | |
| Purified |
| Flow Cytometry | |
| 185-1G2 | |
| PBS | |
| Mouse | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| Recognizes a protein of 80kDa-90kDa, identified as CD36 (Workshop IV; Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This monoclonal antibody blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation. | |
| Store at 4°C in the dark. | |
| IgG2a κ |
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