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CD36 Antibody (185-1G2), PE, Novus Biologicals™

Código de producto. 18027256 Tienda Bio Techne Productos
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Cantidad:
0.1 mL
Tamaño de la unidad:
0.10 ml
Código de producto. Cantidad unitSize
18027256 0.1 mL 0.10 ml
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Código de producto. 18027256

Marca: Novus Biologicals NBP295271PE

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Descripción

Mouse Monoclonal Antibody

CD36 Monoclonal specifically detects CD36 in Human samples. It is validated for Flow Cytometry.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno CD36/SR-B3
Aplicaciones Flow Cytometry
Clasificación Monoclonal
Clon 185-1G2
Conjugado PE
Formulación PBS
Alias de gen CD36 antigen, CD36 molecule (thrombospondin receptor), FA6-152, FATCHDS7, Fatty acid translocase, Glycoprotein IIIb, GP3Bthrombospondin receptor), GPIIIB, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, Platelet collagen receptor, platelet glycoprotein 4, Platelet glycoprotein IV, scavenger receptor class B, member 3, Thrombospondin receptor
Especie del huésped Mouse
Inmunógeno Stimulated human leukocytes
Método de purificación Protein A or G purified
Cantidad 0.1 mL
Estado normativo RUO
Disciplina de investigación Cancer, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Immunology, Lipid and Metabolism, Stem Cell Markers
Primario o secundario Primary
ID de gen (Entrez) 948
Especificidad de la prueba Recognizes a protein of 80kDa-90kDa, identified as CD36 (Workshop IV; Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This monoclonal antibody blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.
Especies diana Human
Contenido y almacenamiento Store at 4°C in the dark.
Formulario Purified
Isotype IgG2a κ
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