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CD34 Antibody (QBEnd/10), Alexa Fluor™ 488, Novus Biologicals™
Mouse Monoclonal Antibody
Marca: Novus Biologicals NBP2-34713AF488
Código de producto. 18016665
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699.00€
660.45€ / 0.10 ml
Ahorro 38.55€
5% Descuento
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Descripción
CD34 Monoclonal specifically detects CD34 in Human, Primate, Bovine (Negative), Canine (Negative), Rat (Negative), Sheep (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Product Image.
Especificaciones
| CD34 | |
| Monoclonal | |
| Alexa Fluor 488 | |
| CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule | |
| Mouse | |
| Protein A purified | |
| RUO | |
| Primary | |
| This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified into three main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but with a lower specificity. | |
| Store at 4C in the dark. | |
| IgG1 κ |
| Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen) | |
| QBEnd/10 | |
| Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen | |
| CD34 | |
| Detergent solubilized vesicular suspension prepared from human term placenta | |
| 0.1 mL | |
| Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors | |
| 947 | |
| Human, Primate, Bovine (Negative), Canine (Negative), Rat (Negative), Sheep (Negative) | |
| Purified |
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Título del producto
For Research Use Only
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