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CD34 Antibody (QBEnd/10), Alexa Fluor™ 488, Novus Biologicals™

Código de producto. 18016665 Tienda Bio Techne Productos
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Cantidad:
0.1 mL
Tamaño de la unidad:
0.10 ml
Código de producto. Cantidad unitSize
18016665 0.1 mL 0.10 ml
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Código de producto. 18016665

Marca: Novus Biologicals NBP234713AF488

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Descripción

Mouse Monoclonal Antibody

CD34 Monoclonal specifically detects CD34 in Human, Primate, Bovine (Negative), Canine (Negative), Rat (Negative), Sheep (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Product Image.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno CD34
Aplicaciones Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clasificación Monoclonal
Clon QBEnd/10
Conjugado Alexa Fluor 488
Dilución Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Alias de gen CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Símbolos de los genes CD34
Especie del huésped Mouse
Inmunógeno Detergent solubilized vesicular suspension prepared from human term placenta
Método de purificación Protein A purified
Cantidad 0.1 mL
Estado normativo RUO
Disciplina de investigación Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors
Primario o secundario Primary
ID de gen (Entrez) 947
Especificidad de la prueba This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified into three main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but with a lower specificity.
Especies diana Human, Primate, Bovine (Negative), Canine (Negative), Rat (Negative), Sheep (Negative)
Contenido y almacenamiento Store at 4C in the dark.
Formulario Purified
Isotype IgG1 κ
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For Research Use Only

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