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CD31 Monoclonal Antibody (CO.3E1D4), FITC, Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA180360
Detalles adicionales : Peso : 0.01000kg
Descripción
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. Mouse anti Sheep CD31 antibody, clone CO.3E1D4 recognizes ovine CD31, also known as PECAM-1.Ovine CD31 is predominantly expressed by peripheral blood platelets and a small percentage of lymphocytes.
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.Especificaciones
CD31 | |
Monoclonal | |
0.1 mg/mL | |
PBS with 1% BSA and 0.09% sodium azide; pH 7.4 | |
P51866 | |
Pecam1 | |
Ovine leucocytes. | |
100 μg | |
Primary | |
Bovine, Goat, Ovine | |
Antibody | |
IgG2a |
Flow Cytometry | |
CO.3E1D4 | |
FITC | |
Pecam1 | |
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule | |
Mouse | |
Protein A | |
RUO | |
100303608, 102179808, 282303 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. | |
Liquid |