missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD3 Mouse, anti-Human, APC, Clone: UCHT1, STEMCELL Technologies
Mouse Monoclonal Antibody
Marca: Stemcell Technologies 100-0448
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
- The UCHT1 antibody reacts with the ∼20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex, which is expressed on the surface of ∼95% of mature T cells and NKT cells, and variably onthymocytes
- A majority of T cell neoplasms also express CD3
- The CD3 complex, which is assembled from combinations of CD3γ, δ, ε, η, and ζ subunits, associates non-covalently with the TCR and is involved in transducing antigen recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR
- Activation of T cells by the TCR involves the cytoplasmic tails of the CD3 subunits, which are structurally related type 1 transmembrane proteins and members of the immunoglobulin superfamily
- Mutations in the CD3 subunits have been associated with various immunodeficiency disorders including severe combined immunodeficiency (SCID)
Especificaciones
| CD3 | |
| Monoclonal | |
| APC | |
| 500 Tests | |
| Chimpanzee, Human |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| UCHT1 | |
| Mouse | |
| Primary | |
| T Cells |
Corrección del contenido de un producto
El Programa Encompass de Fisher Scientific ofrece artículos que no forman parte de nuestra cartera de distribución. Estos productos no suelen tener imágenes ni descripciones detalladas. Sin embargo, nos comprometemos a mejorar su experiencia de compra. Utilice el siguiente formulario para hacernos llegar sus comentarios sobre el contenido de este producto.
Título del producto
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido