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Invitrogen™ Human BRAF, GST Tag Recombinant Protein

Código de producto. p-7180696
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Cantidad:
10 μg
Tamaño de la unidad:
cada uno
Código de producto. Cantidad unitSize
11573577 10 μg cada uno
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Código de producto. 11573577

Marca: Invitrogen™ PV3848

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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in B-Raf have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for B-Raf.
TRUSTED_SUSTAINABILITY

Spécification

Número de acceso P15056
Concentración See Label
Para utilizar con (aplicación) Kinase Assay
Formulación 50mM tris with 150mM NaCl, 0.5mM EDTA, 2mM DTT, 50% glycerol, 0.02% Triton X-100 and no preservative; pH 7.5
ID de gen (Entrez) 673
Peso molecular 113.6 kDa
Nombre Human BRAF, GST Tag
Intervalo de pH 7.5
Método de purificación Purified
Cantidad 10 μg
Requisitos de almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Estado normativo RUO
Alias de gen 94 kDa B-raf protein; 9930012E13Rik; AA120551; AA387315; AA473386; Braf; B-raf; B-raf protein; B-raf protein isoform 1; B-raf protein isoform 2; B-Raf proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf proto-oncogene, serine/threonine kinase; Braf transforming gene; BRAF1; B-RAF1; Braf2; Braf-2; C230098H17; C87398; C-RMIL; D6Ertd631e; FLJ95109; MGC126806; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; Proto-oncogene B-Raf; proto-oncogene c-Rmil; RAFB1; RMIL; rmil serine/threonine-protein kinase; serine/threonine kinase; serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase Rmil; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1
Nombre común B-Raf
Símbolo de gen BRAF
Familia Quinasa RAF Kinase Family
Tipo de producto Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína GST-tag
Secuencia Full length
Contenido y almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Entrada del ensayo Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Grupo de cinasas Ser⁄Thr Kinases: TKL Group
Condiciones de envío Dry Ice
Compatibilidad de sistemas LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate
Entrada diana BRAF
Gen diana v-raf murine sarcoma viral oncogene homolog B1
Sistema de expresión Insect cells
Familia de proteínas Kinases & Inhibitors
Forma de proteína Recombinant, Full Length
Formulario Liquid
Subtipo de proteína Serine/Threonine Kinases
Categoría de investigación Oncology, Signal Transduction
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