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B7-2/CD86 Antibody (BU63), Allophycocyanin, Novus Biologicals™

Código de producto. 18161605 Tienda Bio Techne Productos
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Cantidad:
0.1 mL
Tamaño de la unidad:
0.10 ml
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18161605 0.1 mL 0.10 ml
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Codice prodotto. 18161605 Fornitore Novus Biologicals N. del fornitore NBP234569APC

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Descrizione

Mouse Monoclonal Antibody

B7-2/CD86 Monoclonal specifically detects B7-2/CD86 in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Knockout Validated.
TRUSTED_SUSTAINABILITY

Specifica

Antígeno B7-2/CD86
Aplicaciones Flow Cytometry
Clasificación Monoclonal
Clon BU63
Conjugado APC
Dilución Flow Cytometry
Alias de gen Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86
Símbolos de los genes CD86
Especie del huésped Mouse
Inmunógeno ARH-77 (B-lymphoblastoid cell line)
Peso molecular del antígeno 70 kDa
Método de purificación Protein G purified
Cantidad 0.1 mL
Estado normativo RUO
Disciplina de investigación Adaptive Immunity, Cell Cycle and Replication, Dendritic Cell Markers, Diabetes Research, Immunology
Primario o secundario Primary
ID de gen (Entrez) 942
Especificidad de la prueba Recognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Especies diana Human, Mouse, Rat
Contenido y almacenamiento Store at 4C in the dark.
Formulario Purified
Isotype IgG1 κ
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For Research Use Only

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