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B7-1/CD80 Antibody (IDEC-114 (Galiximab)), DyLight 680, Novus Biologicals™

Código de producto. 18242599 Tienda Bio Techne Productos
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Cantidad:
0.1 mL
Tamaño de la unidad:
0.10 ml
Código de producto. Cantidad unitSize
18242599 0.1 mL 0.10 ml
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Código de producto. 18242599

Proveedor: Novus Biologicals NBP281100FR

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Descripción

Rabbit Monoclonal Antibody

B7-1/CD80 Monoclonal specifically detects B7-1/CD80 in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno B7-1/CD80
Aplicaciones Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
Clasificación Monoclonal
Clon IDEC-114 (Galiximab)
Conjugado DyLight 680
Dilución Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence
Formulación 50mM Sodium Borate
Alias de gen Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen), CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80
Símbolos de los genes CD80
Especie del huésped Rabbit
Inmunógeno Galiximab was prepared by immunizing cynomolgus monkeys with recombinant B7-1/CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)
Método de purificación Protein A purified
Cantidad 0.1 mL
Estado normativo RUO
Disciplina de investigación Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Signal Transduction
Primario o secundario Primary
ID de gen (Entrez) 941
Especificidad de la prueba Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.
Especies diana Human
Contenido y almacenamiento Store at 4°C in the dark.
Formulario Purified
Isotype IgG λ
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