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Invitrogen™ Human AURKA (Aurora A), His Tag Recombinant Protein

Código de producto. 15498453
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Cantidad:
100 μg
Tamaño de la unidad:
100 microgramos
Código de producto. Cantidad unitSize
15498453 100 μg 100 microgramos
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Código de producto. 15498453

Marca: Invitrogen™ PR5935A

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Descripción

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length

AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association in vivo with centrosomes. Overexpression of AURKA is observed in many types of cancer. Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso O14965
Concentración See Label
Para utilizar con (aplicación) Kinase Assay
Formulación 50 mM tris HCl with 0.05% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 4 mM DTT, 50% glycerol and no preservative; pH 7.5
ID de gen (Entrez) 6790
Peso molecular 49.9 kDa
Nombre Human AURKA (Aurora A), His Tag
Cantidad 100 μg
Estado normativo RUO - research use only
Alias de gen Aik; Airk; AIRK1; Ark1; ARK-1; AU019385; AURA; AURAK; AURKA; Aurora 2; aurora A; Aurora A Kinase; aurora family kinase 1; Aurora kinase A; aurora/IP; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; AURORA2; Aurora-A; aurora-related kinase 1; AW539821; Ayk1; Breast tumor-amplified kinase; BTAK; EC 2.7.11.1; hARK1; IAK; IAK1; Ipl1- and aurora-related kinase 1; IPL1-related kinase; MGC34538; OTTHUMP00000031341; OTTHUMP00000166072; PPP1R47; protein phosphatase 1, regulatory subunit 47; ratAurA; RP5-1167H4.6; sereine threonine kinase; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; serine/threonine-protein kinase 6; aurora kinase A; serine/threonine-protein kinase aurora-A; Serine/threonine-protein kinase Ayk1; STK15; STK6; STK7; Unknown (protein for MGC:134472)
Nombre común Aurora A
Familia Quinasa Aurora Kinase Family
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína His-tag
Secuencia Full length
Contenido y almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Sistema de expresión Insect cells
Formulario Liquid
Grado de pureza o calidad 85% by SDS-PAGE
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