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Phospho-GAB2 (Tyr452) Monoclonal Antibody (J.629.4), Invitrogen™
Rabbit Monoclonal Antibody
Marca: Invitrogen MA514923
Detalles adicionales : Peso : 0.01000kg
Descripción
It is not recommended to aliquot this antibody.
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Especificaciones
| Phospho-GAB2 (Tyr452) | |
| Monoclonal | |
| Unconjugated | |
| GAB2 | |
| AI463667; D130058I17Rik; GAB2; Grb2 associated binder 2; GRB2 associated binding protein 2; GRB2-associated binder 2; GRB2-associated binding protein 2; GRB2-associated-binding protein 2; GRB3-3; Growth factor receptor bound protein 2-associated protein 2; KIAA0571; p97; PH domain-containing adaptor molecule p97; pp100 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 14389, 9846 | |
| -20°C | |
| Liquid |
| Western Blot | |
| J.629.4 | |
| 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5 | |
| Q9UQC2, Q9Z1S8 | |
| GAB2 | |
| Synthetic phosphopeptide corresponding to residues surrounding pTyr452 of human Gab2 | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |