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mGluR1 Mouse, Unlabeled, Clone: 20, BD

Mouse Monoclonal Antibody

324.00€ - 565.00€

Especificaciones

Antígeno mGluR1
Clon 20
Concentración 250μg/mL
Aplicaciones Western Blot
Clasificación Monoclonal
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15875729
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BD Biosciences
610964
50 μg
324.00€
1 set
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»
Fecha estimada de envío: 20-06-2024
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15885729
Ver documentos Detalles de la promoción
BD Biosciences
610965
150 μg
565.00€
1 set
Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío: 20-06-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

Glutamate is a major excitatory neurotransmitter and functions in multiple roles in the CNS. The functional diversity of glutamate is exemplified by two distinct groups of glutamate receptors: ionotropic and metabotropic. Coupling with G proteins provides the metabotropic glutamate receptors (mGluRs) with the capacity for intracellular signal transduction. Eight metabotropic glutamate receptors (mGluR1-8) and several Ca2+ sensing receptors belong to a novel G-protein coupled receptor (GPCR) family. The mGluRs possess the seven putative transmembrane domains which are characteristic of GPCR proteins. However, they exhibit no additional sequence homology to any member of other GPCR families. mGluR1 has large hydrophilic sequences in both the N- and C-terminal sides of the seven transmembrane domains. The sizable extracellular N-terminal domain is homologous to bacterial periplasmic binding proteins and serves as the glutamate binding site. mGluR1 activates phospholipase C (PLC), resulting in phosphoinositide turnover and, in turn, Ca2+; mobilization necessary for many signal transduction events.

Immunofluorescence, Western Blotting

Especificaciones

Especificaciones

mGluR1
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
Metabotropic Glutamate Receptor-1
20
Western Blot
Unconjugated
RUO
Mouse, Rat
Rat mGluR1 aa. 1042-1160
Primary
Store undiluted at -20°C.
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Documentos

Documentos

Product Certifications

For Research Use Only.