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Invitrogen™ Human AMPK A2/B1/G1, GST Tag, His Tag Recombinant Protein
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Cantidad:
10 μg
Tamaño de la unidad:
cada uno
Descripción
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.
AMP-activated protein kinase (AMPK) is a heterotrimeric complex that acts as sensor of cellular energy levels. The signaling cascades initiated by activating AMPK are critical to regulating metabolic events in the liver, skeletal muscle, heart, adipose tissue, and pancreas. An impairment in fuel metabolism that occurs in obesity is a factor leading to type 2 diabetes. The insulin resistance associated with type 2 diabetes is most profound at the level of skeletal muscle, the primary site of glucose and fatty acid utilization. Activation of AMPK is of interest for the treatment of type 2 diabetes.
Especificaciones
Especificaciones
| Número de acceso | P54619, P54646, Q9Y478 |
| Concentración | See Label |
| Para utilizar con (aplicación) | Kinase Assay |
| Formulación | 50mM tris with 2mM DTT, 50% glycerol, 0.5mM EDTA, 150mM NaCl, 0.02% Triton X-100 and no preservative; pH 7.5 |
| ID de gen (Entrez) | 5563, 5564, 5571 |
| Peso molecular | 91.4-57.8-41.7 kDa |
| Nombre | Human AMPK A2/B1/G1, GST Tag, His Tag |
| Intervalo de pH | 7.5 |
| Método de purificación | Purified |
| Cantidad | 10 μg |
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