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ACTH Antibody (CLIP/1407), Novus Biologicals™
Mouse Monoclonal Antibody
Marca: Novus Biologicals NBP2-47658-0.1MG
Código de producto. 18107538
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509.00€
480.90€ / 0.10 miligramo
Ahorro 28.10€
5% Descuento
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Descripción
ACTH Monoclonal specifically detects ACTH in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Especificaciones
| ACTH | |
| Monoclonal | |
| Unconjugated | |
| 10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
| ACTH, adrenocorticotropic hormone, adrenocorticotropin, alpha-melanocyte-stimulating hormone, alpha-MSH, beta-endorphin, beta-LPH, beta-melanocyte-stimulating hormone, beta-MSH, CLIP, corticotropin-like intermediary peptide, corticotropin-lipotropin, gamma-LPH, gamma-MSH, lipotropin beta, lipotropin gamma, LPH, melanotropin alpha, melanotropin beta, melanotropin gamma, met-enkephalin, MSH, NPP, POC, pro-ACTH-endorphin, proopiomelanocortin, pro-opiomelanocortin, proopiomelanocortin preproprotein | |
| Mouse | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to CLIP (aa25-39 of ACTH); does not react with Synacthen (aa1-24 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH. | |
| Store at 4C. | |
| IgG |
| Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence | |
| CLIP/1407 | |
| Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry-Paraffin 0.5-1ug/ml, SDS-Page, Immunofluorescence 1-2ug/ml | |
| P01189 | |
| POMC | |
| Synthetic peptide corresponding to aa25-39 of human ACTH (NGAEDESAEAFPLEF) | |
| 0.1 mg | |
| Neuroscience, Nutrient Sensing in the Brain | |
| 5443 | |
| Human | |
| Purified |
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