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Eurofins DiscoverX A-Raf Protein, Active
Description
This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
GenBank U01337.1 The recombinant protein contains the amino acid substitution Y301D and Y302D with reference to GenBank U01337.1. These mutations provide constitutive activation of the enzyme.
Specifications
Specifications
| Formulación | mg/mL of enzyme in 40 mM Tris/HCl pH 8.0, 200 mM NaCl, 0.08 mM EGTA, 0.024% Brij-35, 4 mM glutathione, 20% (v/v) glycerol, 0.8 mM benzamidine, 0.16 mM PMSF, 0.08% 2-mercaptoethanol. Frozen solution. |
| Peso molecular | 65 kDa |
| Cantidad | 250 μg |
| Especie | Human |
| Recombinante | Recombinant |
| Etiqueta de proteína | N-terminal GST |
| Sistema de expresión | Recombinant enzyme expressed in Sf21 insect cells |
| Forma de proteína | Truncated |
| Grado de pureza o calidad | ≥47% |
| Expresión | A-Raf, active |
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