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Eurofins DiscoverX A-Raf Protein, Active

Código de producto. 17320854
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Cantidad:
10 μg
250 μg
Tamaño de la unidad:
10 microgramos
250 microgramos
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Código de producto. 17320854

Marca: Eurofins DiscoverX 14956

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Description

Active, N-terminal GST-tagged, recombinant, human A-Raf, for use in Kinase Assays

This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

GenBank U01337.1 The recombinant protein contains the amino acid substitution Y301D and Y302D with reference to GenBank U01337.1. These mutations provide constitutive activation of the enzyme.

Specifications

Formulación mg/mL of enzyme in 40 mM Tris/HCl pH 8.0, 200 mM NaCl, 0.08 mM EGTA, 0.024% Brij-35, 4 mM glutathione, 20% (v/v) glycerol, 0.8 mM benzamidine, 0.16 mM PMSF, 0.08% 2-mercaptoethanol. Frozen solution.
Peso molecular 65 kDa
Cantidad 10 μg
Especie Human
Recombinante Recombinant
Etiqueta de proteína N-terminal GST
Sistema de expresión Recombinant enzyme expressed in Sf21 insect cells
Forma de proteína Truncated
Grado de pureza o calidad ≥47%
Expresión A-Raf, active
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