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  6. YAP1 Rabbit anti-Human, Mouse, Zebrafish, Polyclonal, Proteintech

YAP1 Rabbit anti-Human, Mouse, Zebrafish, Polyclonal, Proteintech

Product Code. 16821874 Shop All Proteintech Products
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Cantidad:
150 μL
20 μL
Unit Size:
150 microlitros
20 microlitros
Product Code. Cantidad unitSize
16821874 20 μL 20 microlitros
16811874 150 μL 150 microlitros
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Product Code. 16821874

Brand: Proteintech 135841AP20UL

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Description

Rabbit Polyclonal Antibody

This antibody is a rabbit polyclonal antibody. The calculated molecular weight of YAP1 is 54 kDa, but phosphorylated YAP1 is about 65 kDa.

YAP1 (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.

Specifications

Antígeno YAP1
Aplicaciones Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Flow Cytometry, Immunocytochemistry
Clasificación Polyclonal
Concentración 0.3 mg/mL
Conjugado Unconjugated
Formulación PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
génica YAP1
N.º de referencia del gen P46937, P46938, Q1L8J7
Alias de gen 65 kDa Yes associated protein, YAP, YAP1, YAP2, YAP65, YKI, Yorkie homolog
Símbolos de los genes yap1
Especie del huésped Rabbit
Inmunógeno YAP1 Fusion Protein Ag4510
Método de purificación Antigen Affinity Chromatography
Cantidad 20 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 10413, 22601, 561411
Especies diana Zebrafish, Human, Mouse
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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