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Invitrogen™ YAP1 Polyclonal Antibody
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Código de producto. 11598980
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
11598980 100 μL 100 microlitros
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Código de producto. 11598980

Marca: Invitrogen™ PA146189

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Descripción

Rabbit Polyclonal Antibody

Suggested positive control: brain and kidney lysates, and HEK 293 cell lysate, 293 whole cell lysate, antigen standard for YAP1 (transient overexpression lysate), human kidney protein, human brain protein.

YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.
TRUSTED_SUSTAINABILITY

Specifica

Antígeno YAP1
Aplicaciones ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Clasificación Polyclonal
Concentración 1.0 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.02% sodium azide
génica YAP1
N.º de referencia del gen P46937, P46938, Q1L8J7, Q2EJA0
Alias de gen 65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP
Símbolos de los genes YAP1
Especie del huésped Rabbit
Inmunógeno Partial recombinant human YAP1 protein expressed in bacteria.
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 10413, 22601, 363014, 479465, 561411
Especies diana Canine, Human, Mouse, Rat, Zebrafish
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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Titolo del prodotto
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