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Invitrogen™ XRCC3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA116535
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Descripción
This antibody is specific for XRCC3; no cross-reactivity was observed with XRCC2, RAD51, RAD51B, RAD51C, or RAD51D. This antibody is not recommended for ICC/IF applications. Suggested positive control: antigen standard for XRCC3 (transient overexpression lysate), TK6 lysates and 100 μg HeLa lysates.
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
Especificaciones
| XRCC3 | |
| Polyclonal | |
| Unconjugated | |
| XRCC3 | |
| 4432412E01Rik; AI182522; AW537713; CMM6; DNA repair protein XRCC3; DNA repair protein XRCC3-like; LOC102551085; RAD51 like; X-ray repair complementing defective repair in Chinese hamster cells 3; X-ray repair cross complementing 3; X-ray repair cross-complementing protein 3; XRCC 3; XRCC3 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 103161145, 7517 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| O43542 | |
| XRCC3 | |
| A synthetic partial peptide of human XRCC3. | |
| 100 μL | |
| Primary | |
| Human, Hamster, Drosophila | |
| Antibody | |
| IgG |
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