missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ XAF1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA520038
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
In Western blot applications, this antibody detects a band at ~32kDa. A suggested positive control is human spleen tissue lysate. PA5-20038 can be used with blocking peptide PEP-0157.
The inhibitors of apoptosis (IAP) proteins prevent cell death both in vitro and in vivo by virtue of inhibition of distinct caspases. The X-linked Inhibitor of Apoptosis, XIAP, is a key member of the IAP family of proteins. The caspase inhibiting activity of XIAP is negatively regulated by at least two XIAP-interacting proteins, XIAP-associated factor 1 (XAF1) and Smac/DIABLO. XAF1 binds to XIAP and antagonizes caspase inhibitory activities of XIAP. Expression of XAF1 triggers a redistribution of XIAP from the cytosol to the nucleus. XAF1 is ubiquitously expressed in normal tissues, but is present at low or undetectable levels in many different cancer cell lines.
Especificaciones
| XAF1 | |
| Polyclonal | |
| Unconjugated | |
| XAF1 | |
| BIRC4 binding protein; BIRC4-binding protein; Birc4bp; F-box protein 39; Fbox39; HSXIAPAF1; novel TRAF-type zinc finger protein; XAF1; XIAP associated factor 1; XIAP associated factor-1; Xiapaf1; XIAP-associated factor 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 327959, 54739 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q5NBU8, Q6GPH4 | |
| XAF1 | |
| A synthetic peptide corresponding to amino acids at the C-terminus of human XAF-1. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido