missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ XAF1 Polyclonal Antibody

Descripción
Immunogen sequence: PVECKFCKLD MQLSKLELHE SYCGSRTELC QGCGQFIMHR MLAQHRDVCR SEQAQLGKGE RISAPEREIY CHYC Highest antigen sequence indentity to the following orthologs: Rat - 50%, Mouse - 48%.
The inhibitors of apoptosis (IAP) proteins prevent cell death both in vitro and in vivo by virtue of inhibition of distinct caspases. The X-linked Inhibitor of Apoptosis, XIAP, is a key member of the IAP family of proteins. The caspase inhibiting activity of XIAP is negatively regulated by at least two XIAP-interacting proteins, XIAP-associated factor 1 (XAF1) and Smac/DIABLO. XAF1 binds to XIAP and antagonizes caspase inhibitory activities of XIAP. Expression of XAF1 triggers a redistribution of XIAP from the cytosol to the nucleus. XAF1 is ubiquitously expressed in normal tissues, but is present at low or undetectable levels in many different cancer cell lines.
Especificaciones
Especificaciones
| Antígeno | XAF1 |
| Aplicaciones | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.3 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | XAF1 |
| N.º de referencia del gen | Q6GPH4 |
| Alias de gen | BIRC4 binding protein; BIRC4-binding protein; Birc4bp; F-box protein 39; Fbox39; HSXIAPAF1; novel TRAF-type zinc finger protein; XAF1; XIAP associated factor 1; XIAP associated factor-1; Xiapaf1; XIAP-associated factor 1 |
| Símbolos de los genes | XAF1 |
| Mostrar más |
Título del producto
Al hacer clic en Enviar, acepta que Fisher Scientific se ponga en contacto con usted en relación con los comentarios que ha proporcionado en este formulario. No compartiremos su información para ningún otro fin. Toda la información de contacto proporcionada se mantendrá de acuerdo con nuestra Política de Privacidad. Política de privacidad.
¿Detecta una oportunidad de mejora?