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Invitrogen™ VPS51 Polyclonal Antibody

Código de producto. 15746741 Tienda Thermo Scientific Productos
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
15746741 100 μL 100 microlitros
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Código de producto. 15746741

Marca: Invitrogen™ PA558869

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FDPEVYLDKL RRECPLAQLM DSETDMVRQI RALDSDMQTL VYENYNKFIS ATDTIRKMKN DFRKMEDEMD RLATNMAVIT DFS Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno VPS51
Aplicaciones Immunohistochemistry (Paraffin), Western Blot
Clasificación Polyclonal
Concentración 0.3 mg/mL
Conjugado Unconjugated
Formulación PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
génica VPS51
N.º de referencia del gen Q9UID3
Alias de gen 1110014N23Rik; 3110057M17Rik; AI837850; ANG2; ANG3; Another new gene 2 protein; C11orf2; C11orf3; Ffr; PP5382; Protein fat-free homolog; vacuolar protein sorting 51 homolog; vacuolar protein sorting 51 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 51 homolog; VPS51; VPS51 GARP complex subunit; VPS51, GARP complex subunit
Símbolos de los genes VPS51
Especie del huésped Rabbit
Inmunógeno Recombinant protein corresponding to Human VPS51. Recombinant protein control fragment (Product #RP-97383).
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 738
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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