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Invitrogen™ BRG1 Monoclonal Antibody (GT2712)

Mouse Monoclonal Antibody
Marca: Invitrogen™ MA531550
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Descripción
Keep as concentrated solution. Predicted reactivity: Mouse (100%), Rat (100%), Chicken (84%), Bovine (87%). Positive Control: 293T, K562, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.
Especificaciones
| BRG1 | |
| Monoclonal | |
| 2.44 mg/mL | |
| PBS with no preservative | |
| P51532, Q3TKT4, Q8K1P7 | |
| Smarca4 | |
| Recombinant protein encompassing a sequence within the N-terminus region of human BRG1. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| GT2712 | |
| Unconjugated | |
| Smarca4 | |
| ATP-dependent helicase SMARCA4; b2b508.1Clo; b2b692Clo; BAF190; BAF190A; brahma protein-like 1; BRG1; brg-1; BRG1-associated factor 190A; BRM/SWI2-related gene 1; CSS4; FLJ39786; global transcription activator homologous sequence; homeotic gene regulator; HP1-BP72; hSNF2b; mitotic growth and transcription activator; MRD16; nuclear protein GRB1; protein brahma homolog 1; Protein BRG-1; RTPS2; SMARCA4; SNF2; Snf2b; SNF2beta; SNF2-beta; SNF2L4; SNF2LB; SNF2-like 4; sucrose nonfermenting-like 4; SW1/SNF; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; SWI2; transcription activator BRG1 | |
| Mouse | |
| Protein G | |
| RUO | |
| 171379, 20586, 6597 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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